An X linked trait that results due to hormonal insensitivity of target cells:
Correct answer: C. Testicular feminization syndrome
- A. Gout
- B. Duchenne muscular dystrophy
- C. Testicular feminization syndrome
- D. Color blindness
Explanation
Tfn gene encodes a receptor for a hormone known as androgen. Androgens are unable to bind to receptors when the mutated tfm gene fails to code for receptors. Androgen insensitivity (testicular feminization) syndrome is a rare inherited form of male pseudohermaphroditism that occurs in phenotypically normal women with adequate breast development, normal external genitalia, a vagina of variable depth, absent uterus, and sparse or absent pubic hair and axillary hair.
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About Inheritance
Mendel's laws explain segregation, independent assortment and the prediction of genetic ratios using alleles, genotypes and phenotypes. The chapter also covers linked genes, recombination and crossing over during meiosis, then applies pedigree reasoning to X-linked recessive traits, which show different inheritance patterns in males and females.
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