Moderate

Activation of which one of the following coagulation factors is not essential for hemostasis________________?

Correct answer: A. XII

  • A. XII
  • B. XI
  • C. IX
  • D. X

Explanation

Factor XII initiates the contact pathway in laboratory testing but is not essential for normal hemostasis in vivo, because tissue-factor-mediated coagulation can generate clotting. Factors XI, IX and X have more important roles in effective coagulation.

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