Accumulation of NADH inhibits the Krebs cycle by inhibiting:
Correct answer: B. Pyruvate decarboxylase
- A. Phosphoglucokinase
- B. Pyruvate decarboxylase
- C. Phosphofructokinase
- D. Pyruvate dehydrogenase
Explanation
If pyruvate decarboxylase is inhibited acetate formation and subsequently Acetyl Co. A formation will be stopped. As a result Kreb's cycle will be stopped from the beginning. It is called negative feedback or feedback inhibition.
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About Bioenergetics
Cellular respiration explains how cells release energy from glucose through glycolysis, the link reaction, Krebs cycle and electron transport chain. It includes ATP production, substrate-level and oxidative phosphorylation, aerobic versus anaerobic respiration, and the roles of mitochondria, oxygen and fermentation in energy transfer.
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