A son of a carrier daughter will be affected by hemophilia if he inherits the X-chromosome of:
Correct answer: B. Maternal grandfather or maternal grandmother
- A. Maternal grandmother or paternal grandmother
- B. Maternal grandfather or maternal grandmother
- C. Paternal grandmother or paternal grandfather
- D. Paternal grandfather, maternal grandfather
Explanation
Xh is inherited by a male directly from his affected or carrier mother. However, the mother has inherited it from her father or mother. Thus the male will inherit it directly from the mother's father or mother's mother.
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About Inheritance
Mendel's laws explain segregation, independent assortment and the prediction of genetic ratios using alleles, genotypes and phenotypes. The chapter also covers linked genes, recombination and crossing over during meiosis, then applies pedigree reasoning to X-linked recessive traits, which show different inheritance patterns in males and females.
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