A patient with chronic kidney disease has persistent fatigue and a hemoglobin level of 8.5 g/dL. Which explanation best describes the likely cause?

Correct answer: A. Reduced production of erythropoietin by the kidneys

  • A. Reduced production of erythropoietin by the kidneys
  • B. Increased production of erythropoietin by the liver
  • C. Excessive destruction of platelets in the spleen
  • D. Increased absorption of iron from the intestine

Explanation

Diseased kidneys produce less erythropoietin, so the bone marrow receives less stimulation to make red blood cells. This causes a normocytic anemia and fatigue. Iron deficiency may also occur, but it is not the main mechanism of anemia in chronic kidney disease.

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About Renal and Urological Nursing

Covers assessment and care for urinary tract infection, glomerulonephritis, nephrotic syndrome, acute kidney injury, chronic kidney disease, renal stones and urinary obstruction. The subject includes intake and output, urinalysis, fluid restriction, dialysis care and the difference between prerenal, intrinsic and postrenal kidney injury.

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