A patient with central diabetes insipidus begins desmopressin therapy. Which finding requires prompt reporting as a possible adverse effect?

Correct answer: C. The patient gains weight rapidly and develops a headache

  • A. Urine output decreases to a normal amount
  • B. The patient reports mild thirst before lunch
  • C. The patient gains weight rapidly and develops a headache
  • D. Urine becomes less dilute during treatment

Explanation

Desmopressin reduces excessive urine loss, but too much water retention can cause hyponatraemia. Rapid weight gain and headache may be early signs of water intoxication and require prompt assessment. A more normal urine output and reduced dilution are expected therapeutic effects.

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About Endocrine and Diabetes Nursing

Covers diabetes mellitus, insulin therapy, hypoglycaemia, diabetic ketoacidosis, hyperosmolar states and common thyroid, adrenal and pituitary disorders. It includes blood glucose monitoring, diet, foot care, sick-day management and the clinical differences between type 1 and type 2 diabetes and between diabetic ketoacidosis and hyperosmolar hyperglycaemic state.

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