A patient receives an antibiotic that requires monitoring of its blood concentration. The nurse collects the blood sample immediately before the next scheduled dose. Which drug concentration is being measured?
Correct answer: B. Trough concentration
- A. Peak concentration
- B. Trough concentration
- C. Loading concentration
- D. Therapeutic response
Explanation
A trough concentration is the lowest drug level in the blood and is measured just before the next dose. A peak concentration is collected after dosing when the drug level is expected to be highest, while the other options are not names for this sampling time.
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About Principles of Pharmacology
Pharmacology examines drug sources, names, dosage forms, mechanisms of action, absorption, distribution, metabolism and excretion. Questions cover pharmacokinetics versus pharmacodynamics, therapeutic effects, adverse reactions, contraindications, drug interactions, tolerance, dependence and the safety responsibilities of the nurse.
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