A patient needs increasing amounts of an opioid over time to obtain the same level of pain relief. Which concept does this finding demonstrate?
Correct answer: A. Tolerance
- A. Tolerance
- B. Idiosyncratic reaction
- C. Drug allergy
- D. Therapeutic antagonism
Explanation
Tolerance is a reduced response to a drug after repeated exposure, causing a need for a larger dose to achieve the previous effect. Dependence is different because it refers to withdrawal symptoms when the drug is stopped.
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About Principles of Pharmacology
Pharmacology examines drug sources, names, dosage forms, mechanisms of action, absorption, distribution, metabolism and excretion. Questions cover pharmacokinetics versus pharmacodynamics, therapeutic effects, adverse reactions, contraindications, drug interactions, tolerance, dependence and the safety responsibilities of the nurse.
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