A patient has prolonged exposure to a high concentration of a hormone. Which cellular response may reduce the hormone's effect over time?
Correct answer: A. Decreased receptor number
- A. Decreased receptor number
- B. Increased receptor number
- C. Increased hormone synthesis
- D. Increased target-cell sensitivity
Explanation
Persistent high hormone levels can cause down-regulation, in which target cells reduce the number of receptors available. This lowers cellular responsiveness and helps limit overstimulation.
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About Endocrine System
The endocrine system covers hormone-producing glands including the pituitary, thyroid, parathyroids, adrenals, pancreas, pineal gland, ovaries and testes. It explains hormone classes, target-cell responses, feedback control, and the functions of hormones such as insulin, thyroxine, cortisol, growth hormone and ADH, which is often confused with a kidney-produced substance.
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