A patient has primary adrenal insufficiency. Which change in pituitary hormone secretion is expected because of reduced negative feedback?
Correct answer: A. Increased ACTH secretion
- A. Increased ACTH secretion
- B. Decreased ACTH secretion
- C. Increased ADH breakdown
- D. Decreased TSH release
Explanation
Low cortisol reduces negative feedback on the hypothalamus and anterior pituitary, so ACTH secretion increases. ACTH is not expected to fall when adrenal cortisol production is inadequate.
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About Endocrine System
The endocrine system covers hormone-producing glands including the pituitary, thyroid, parathyroids, adrenals, pancreas, pineal gland, ovaries and testes. It explains hormone classes, target-cell responses, feedback control, and the functions of hormones such as insulin, thyroxine, cortisol, growth hormone and ADH, which is often confused with a kidney-produced substance.
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