The cause of testicular feminization syndrome is:
Correct answer: A. A recessive gene on X-chromosome
- A. A recessive gene on X-chromosome
- B. A recessive gene on Y-chromosome
- C. A dominant gene on X-chromosome
- D. A dominant gene on Y-chromosome
Explanation
The cause of testicular feminization syndrome (TFS) is a mutation in the androgen receptor gene. This gene is responsible for sending signals to the body's cells to respond to androgens. If the androgen receptor gene is mutated, the body's cells will not be able to respond to androgens, and the person will develop the features of TFS.The androgen receptor gene is located on the X chromosome. This means that TFS is an X-linked recessive disorder. This means that a person must inherit two copies of the mutated gene in order to have TFS. If a person inherits only one copy of the mutated gene, they will be a carrier of the disorder, but they will not show any symptoms.
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About Inheritance
Mendel's laws explain segregation, independent assortment and the prediction of genetic ratios using alleles, genotypes and phenotypes. The chapter also covers linked genes, recombination and crossing over during meiosis, then applies pedigree reasoning to X-linked recessive traits, which show different inheritance patterns in males and females.
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