Albinism is a congenital disorder resulting from the lack of which enzyme?
Correct answer: A. Tyrosinase
- A. Tyrosinase
- B. Xanthine oxidase
- C. Catalase
- D. Fructokinase
Explanation
Albinism is a genetic condition characterized by the absence of melanin, the pigment responsible for coloration in the skin, hair, and eyes. This condition results from mutations in the gene responsible for producing tyrosinase, an enzyme critical for melanin synthesis. In albinism, the gene's mutation leads to a nonfunctional tyrosinase enzyme, preventing melanin production.Option A, Tyrosinase, is correct because it is the enzyme whose deficiency directly causes albinism. Option B, Xanthine oxidase, is unrelated to melanin production and instead affects purine metabolism. Option C, Catalase, is involved in breaking down hydrogen peroxide and is not linked to melanin or albinism. Option D, Fructokinase, affects fructose metabolism and is unrelated to the condition in question.
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Mendel's laws explain segregation, independent assortment and the prediction of genetic ratios using alleles, genotypes and phenotypes. The chapter also covers linked genes, recombination and crossing over during meiosis, then applies pedigree reasoning to X-linked recessive traits, which show different inheritance patterns in males and females.
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