Ahmed's blood could not clot properly; he was diagnosed with hemophilia A. He passed this trait to his grandson through his:
Correct answer: C. Daughter
- A. Wife
- B. Son
- C. Daughter
- D. Brother
Explanation
X chromosome of the father is only transferred to the daughter, a son takes the Y chromosome and hemophilia is an X-linked disease Ahmed, who has hemophilia A, a condition where blood does not clot properly, can pass this trait to his grandson through his daughter. Hemophilia A is an X-linked recessive disorder, meaning that the gene responsible for the condition is located on the X chromosome. Since Ahmed is the grandfather, he must pass on his X chromosome to his daughter. If his daughter inherits the affected X chromosome from Ahmed, she becomes a carrier of hemophilia A. As a carrier, she has one normal X chromosome and one affected X chromosome, but since hemophilia A is a recessive trait, she does not show symptoms of the condition. When the daughter has a child (Ahmed's grandson), she has a 50% chance of passing on the affected X chromosome to her son. If the affected X chromosome is passed on, the grandson would inherit the hemophilia A trait and potentially experience clotting problems. It's important to note that if the daughter does not pass on the affected X chromosome to her son, he will not inherit hemophilia A. However, he would still be a carrier of the condition, meaning he could potentially pass it on to his own offspring if he has children in the future.
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About Inheritance
Mendel's laws explain segregation, independent assortment and the prediction of genetic ratios using alleles, genotypes and phenotypes. The chapter also covers linked genes, recombination and crossing over during meiosis, then applies pedigree reasoning to X-linked recessive traits, which show different inheritance patterns in males and females.
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